Ketamine activates adult-born immature granule neurons to rapidly alleviate depression-like behaviors in mice

Ketamine treatment decreases depressive symptoms within hours, but the mechanisms mediating these rapid antidepressant effects are unclear. Here, we demonstrate that activity of adult-born immature granule neurons (ABINs) in the mouse hippocampal dentate gyrus is both necessary and sufficient for th...

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Detalles Bibliográficos
Autores principales: Rawat, Radhika, Tunc-Ozcan, Elif, McGuire, Tammy L., Peng, Chian-Yu, Kessler, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098911/
https://www.ncbi.nlm.nih.gov/pubmed/35551462
http://dx.doi.org/10.1038/s41467-022-30386-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098911/
https://www.ncbi.nlm.nih.gov/pubmed/35551462
http://dx.doi.org/10.1038/s41467-022-30386-5

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