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Ketamine activates adult-born immature granule neurons to rapidly alleviate depression-like behaviors in mice
Ketamine treatment decreases depressive symptoms within hours, but the mechanisms mediating these rapid antidepressant effects are unclear. Here, we demonstrate that activity of adult-born immature granule neurons (ABINs) in the mouse hippocampal dentate gyrus is both necessary and sufficient for th...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9098911/ https://www.ncbi.nlm.nih.gov/pubmed/35551462 http://dx.doi.org/10.1038/s41467-022-30386-5 |