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Auditory and Vestibular Characteristics of NLRP3 Inflammasome Related Autoinflammatory Disorders: Monogenic Hearing Loss Can Be Improved by Anti-interleukin-1 Therapy

Inflammasomes are large multimeric protein complexes which regulate the activation of the proinflammatory cytokines interleukins-1β and−18 and inflammatory cell death called pyroptosis. NLRP1, NLRP3, NLRC4, AIM2, and pyrin can induce the formation of inflammasomes. Of these, the NLRP3 inflammasome i...

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Detalles Bibliográficos
Autores principales: Nakanishi, Hiroshi, Yamada, Satoshi, Kita, Junya, Shinmura, Daichi, Hosokawa, Kumiko, Sahara, Sosuke, Misawa, Kiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099043/
https://www.ncbi.nlm.nih.gov/pubmed/35572943
http://dx.doi.org/10.3389/fneur.2022.865763