V(D)J Recombination: Recent Insights in Formation of the Recombinase Complex and Recruitment of DNA Repair Machinery

V(D)J recombination is an essential mechanism of the adaptive immune system, producing a diverse set of antigen receptors in developing lymphocytes via regulated double strand DNA break and subsequent repair. DNA cleavage is initiated by the recombinase complex, consisting of lymphocyte specific pro...

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Detalles Bibliográficos
Autores principales: Christie, Shaun M., Fijen, Carel, Rothenberg, Eli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099191/
https://www.ncbi.nlm.nih.gov/pubmed/35573672
http://dx.doi.org/10.3389/fcell.2022.886718

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099191/
https://www.ncbi.nlm.nih.gov/pubmed/35573672
http://dx.doi.org/10.3389/fcell.2022.886718

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