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Polymorphisms of Cytochromes P450 and Glutathione S-Transferases Synergistically Modulate Risk for Parkinson’s Disease

BACKGROUND: Environmental substances such as pesticides are well-known in link with Parkinson’s disease (PD) risk. Enzymes including cytochromes P450 (CYPs), esterases and glutathione S-transferases (GSTs) are responsible for the xenobiotic metabolism and may functionally compensate each other for s...

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Detalles Bibliográficos
Autores principales: Fan, Hui-Hui, Li, Bao-Qing, Wu, Ke-Yun, Yan, Hai-Dan, Gu, Meng-Jie, Yao, Xing-Hao, Dong, Hao-Jia, Zhang, Xiong, Zhu, Jian-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099289/
https://www.ncbi.nlm.nih.gov/pubmed/35572141
http://dx.doi.org/10.3389/fnagi.2022.888942