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A Simple and Sensitive UPLC–UV Method for Simultaneous Determination of Isoniazid, Pyrazinamide, and Rifampicin in Human Plasma and Its Application in Therapeutic Drug Monitoring

As the first-line clinical drugs for tuberculosis (TB), isoniazid (INH), pyrazinamide (PZA), and rifampicin (RMP) are playing important roles for preventing the rapid spread of TB. Precise quantification of these drugs in biological samples is crucial to evaluate or improve the efficacy of advanced...

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Detalles Bibliográficos
Autores principales: Jiang, Zhimei, Huang, Liang, Zhang, Lingli, Yu, Qin, Lin, Yunzhu, Fei, Haotian, Shen, Hongxin, Huang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099412/
https://www.ncbi.nlm.nih.gov/pubmed/35573738
http://dx.doi.org/10.3389/fmolb.2022.873311