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BRD2 Compartmentalizes the Accessible Genome

Mammalian chromosomes are organized into megabase-sized compartments that are further subdivided into topologically associated domains (TADs). While the formation of TADs is dependent on Cohesin, the mechanism behind compartmentalization remains enigmatic. Here, we show that the bromodomain and extr...

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Detalles Bibliográficos
Autores principales: Xie, Liangqi, Dong, Peng, Qi, Yifeng, Hsieh, Tsung-Han S., English, Brian P., Jung, SeolKyoung, Chen, Xingqi, De Marzio, Margherita, Casellas, Rafael, Chang, Howard Y., Zhang, Bin, Tjian, Robert, Liu, Zhe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099420/
https://www.ncbi.nlm.nih.gov/pubmed/35410381
http://dx.doi.org/10.1038/s41588-022-01044-9