Combining Pharmacokinetics and Vibrational Spectroscopy: MCR-ALS Hard-and-Soft Modelling of Drug Uptake In Vitro Using Tailored Kinetic Constraints

Raman microspectroscopy is a label-free technique which is very suited for the investigation of pharmacokinetics of cellular uptake, mechanisms of interaction, and efficacies of drugs in vitro. However, the complexity of the spectra makes the identification of spectral patterns associated with the d...

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Detalles Bibliográficos
Autores principales: Pérez-Guaita, David, Quintás, Guillermo, Farhane, Zeineb, Tauler, Romá, Byrne, Hugh J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099467/
https://www.ncbi.nlm.nih.gov/pubmed/35563861
http://dx.doi.org/10.3390/cells11091555

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099467/
https://www.ncbi.nlm.nih.gov/pubmed/35563861
http://dx.doi.org/10.3390/cells11091555

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