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FKBP51, AmotL2 and IQGAP1 Involvement in Cilastatin Prevention of Cisplatin-Induced Tubular Nephrotoxicity in Rats

The immunophilin FKBP51, the angiomotin AmotL2, and the scaffoldin IQGAP1 are overexpressed in many types of cancer, with the highest increase in leucocytes from patients undergoing oxaliplatin chemotherapy. Inflammation is involved in the pathogenesis of nephrotoxicity induced by platinum analogs....

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Detalles Bibliográficos
Autores principales: González-Fernández, Rebeca, González-Nicolás, María Ángeles, Morales, Manuel, Ávila, Julio, Lázaro, Alberto, Martín-Vasallo, Pablo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099571/
https://www.ncbi.nlm.nih.gov/pubmed/35563891
http://dx.doi.org/10.3390/cells11091585