Glucocorticoid Receptor β Isoform Predominates in the Human Dysplastic Brain Region and Is Modulated by Age, Sex, and Antiseizure Medication

The glucocorticoid receptor (GR) at the blood–brain barrier (BBB) is involved in the pathogenesis of drug-resistant epilepsy with focal cortical dysplasia (FCD); however, the roles of GR isoforms GRα and GRβ in the dysplastic brain have not been revealed. We utilized dysplastic/epileptic and non-dys...

Descripción completa

Detalles Bibliográficos
Autores principales: Westcott, Rosemary, Chung, Natalie, Ghosh, Arnab, Ferguson, Lisa, Bingaman, William, Najm, Imad M., Ghosh, Chaitali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099578/
https://www.ncbi.nlm.nih.gov/pubmed/35563330
http://dx.doi.org/10.3390/ijms23094940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099578/
https://www.ncbi.nlm.nih.gov/pubmed/35563330
http://dx.doi.org/10.3390/ijms23094940

Ejemplares similares