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Glucocorticoid Receptor β Isoform Predominates in the Human Dysplastic Brain Region and Is Modulated by Age, Sex, and Antiseizure Medication
The glucocorticoid receptor (GR) at the blood–brain barrier (BBB) is involved in the pathogenesis of drug-resistant epilepsy with focal cortical dysplasia (FCD); however, the roles of GR isoforms GRα and GRβ in the dysplastic brain have not been revealed. We utilized dysplastic/epileptic and non-dys...
Autores principales: | Westcott, Rosemary, Chung, Natalie, Ghosh, Arnab, Ferguson, Lisa, Bingaman, William, Najm, Imad M., Ghosh, Chaitali |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099578/ https://www.ncbi.nlm.nih.gov/pubmed/35563330 http://dx.doi.org/10.3390/ijms23094940 |
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