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Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update
Perilla, also termed as purple mint, Chinese basil, or Perilla mint, is a flavoring herb widely used in East Asia. Both crude oil and essential oil are employed for consumption as well as industrial purposes. Fatty acids (FAs) biosynthesis and oil body assemblies in Perilla have been extensively inv...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099743/ https://www.ncbi.nlm.nih.gov/pubmed/35567213 http://dx.doi.org/10.3390/plants11091207 |
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author | Bae, Seon-Hwa Zoclanclounon, Yedomon Ange Bovys Kumar, Thamilarasan Senthil Oh, Jae-Hyeon Lee, Jundae Kim, Tae-Ho Park, Ki Young |
author_facet | Bae, Seon-Hwa Zoclanclounon, Yedomon Ange Bovys Kumar, Thamilarasan Senthil Oh, Jae-Hyeon Lee, Jundae Kim, Tae-Ho Park, Ki Young |
author_sort | Bae, Seon-Hwa |
collection | PubMed |
description | Perilla, also termed as purple mint, Chinese basil, or Perilla mint, is a flavoring herb widely used in East Asia. Both crude oil and essential oil are employed for consumption as well as industrial purposes. Fatty acids (FAs) biosynthesis and oil body assemblies in Perilla have been extensively investigated over the last three decades. Recent advances have been made in order to reveal the enzymes involved in the fatty acid biosynthesis in Perilla. Among those fatty acids, alpha-linolenic acid retained the attention of scientists mainly due to its medicinal and nutraceutical properties. Lipids synthesis in Perilla exhibited similarities with Arabidopsis thaliana lipids’ pathway. The homologous coding genes for polyunsaturated fatty acid desaturases, transcription factors, and major acyl-related enzymes have been found in Perilla via de novo transcriptome profiling, genome-wide association study, and in silico whole-genome screening. The identified genes covered de novo fatty acid synthesis, acyl-CoA dependent Kennedy pathway, acyl-CoA independent pathway, Triacylglycerols (TAGs) assembly, and acyl editing of phosphatidylcholine. In addition to the enzymes, transcription factors including WRINKLED, FUSCA3, LEAFY COTYLEDON1, and ABSCISIC ACID INSENSITIVE3 have been suggested. Meanwhile, the epigenome aspect impacting the transcriptional regulation of FAs is still unclear and might require more attention from the scientific community. This review mainly outlines the identification of the key gene master players involved in Perilla FAs biosynthesis and TAGs assembly that have been identified in recent years. With the recent advances in genomics resources regarding this orphan crop, we provided an updated overview of the recent contributions into the comprehension of the genetic background of fatty acid biosynthesis. The provided resources can be useful for further usage in oil-bioengineering and the design of alpha-linolenic acid-boosted Perilla genotypes in the future. |
format | Online Article Text |
id | pubmed-9099743 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-90997432022-05-14 Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update Bae, Seon-Hwa Zoclanclounon, Yedomon Ange Bovys Kumar, Thamilarasan Senthil Oh, Jae-Hyeon Lee, Jundae Kim, Tae-Ho Park, Ki Young Plants (Basel) Review Perilla, also termed as purple mint, Chinese basil, or Perilla mint, is a flavoring herb widely used in East Asia. Both crude oil and essential oil are employed for consumption as well as industrial purposes. Fatty acids (FAs) biosynthesis and oil body assemblies in Perilla have been extensively investigated over the last three decades. Recent advances have been made in order to reveal the enzymes involved in the fatty acid biosynthesis in Perilla. Among those fatty acids, alpha-linolenic acid retained the attention of scientists mainly due to its medicinal and nutraceutical properties. Lipids synthesis in Perilla exhibited similarities with Arabidopsis thaliana lipids’ pathway. The homologous coding genes for polyunsaturated fatty acid desaturases, transcription factors, and major acyl-related enzymes have been found in Perilla via de novo transcriptome profiling, genome-wide association study, and in silico whole-genome screening. The identified genes covered de novo fatty acid synthesis, acyl-CoA dependent Kennedy pathway, acyl-CoA independent pathway, Triacylglycerols (TAGs) assembly, and acyl editing of phosphatidylcholine. In addition to the enzymes, transcription factors including WRINKLED, FUSCA3, LEAFY COTYLEDON1, and ABSCISIC ACID INSENSITIVE3 have been suggested. Meanwhile, the epigenome aspect impacting the transcriptional regulation of FAs is still unclear and might require more attention from the scientific community. This review mainly outlines the identification of the key gene master players involved in Perilla FAs biosynthesis and TAGs assembly that have been identified in recent years. With the recent advances in genomics resources regarding this orphan crop, we provided an updated overview of the recent contributions into the comprehension of the genetic background of fatty acid biosynthesis. The provided resources can be useful for further usage in oil-bioengineering and the design of alpha-linolenic acid-boosted Perilla genotypes in the future. MDPI 2022-04-29 /pmc/articles/PMC9099743/ /pubmed/35567213 http://dx.doi.org/10.3390/plants11091207 Text en © 2022 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Bae, Seon-Hwa Zoclanclounon, Yedomon Ange Bovys Kumar, Thamilarasan Senthil Oh, Jae-Hyeon Lee, Jundae Kim, Tae-Ho Park, Ki Young Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update |
title | Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update |
title_full | Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update |
title_fullStr | Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update |
title_full_unstemmed | Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update |
title_short | Advances in Understanding the Genetic Basis of Fatty Acids Biosynthesis in Perilla: An Update |
title_sort | advances in understanding the genetic basis of fatty acids biosynthesis in perilla: an update |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099743/ https://www.ncbi.nlm.nih.gov/pubmed/35567213 http://dx.doi.org/10.3390/plants11091207 |
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