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Global 5mC and 5hmC DNA Levels in Human Sperm Subpopulations with Differentially Protaminated Chromatin in Normo- and Oligoasthenozoospermic Males

Epigenetic modifications play a special role in the male infertility aetiology. Published data indicate the link between sperm quality and sperm chromatin protamination. This study aimed to determine the relationship between methylation (5mC) and hydroxymethylation (5hmC) in sperm DNA, with respect...

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Detalles Bibliográficos
Autores principales: Olszewska, Marta, Kordyl, Oliwia, Kamieniczna, Marzena, Fraczek, Monika, Jędrzejczak, Piotr, Kurpisz, Maciej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099774/
https://www.ncbi.nlm.nih.gov/pubmed/35562907
http://dx.doi.org/10.3390/ijms23094516