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Role of Presenilin-1 in Aggressive Human Melanoma

Presenilin-1 (PS-1), a component of the gamma (γ)-secretase catalytic complex, has been implicated in Alzheimer’s disease (AD) and in tumorigenesis. Interestingly, AD risk is inversely related to melanoma, suggesting that AD-related factors, such as PS-1, may affect melanomagenesis. PS-1 has been sh...

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Detalles Bibliográficos
Autores principales: Sidor, Julia, Gillette, Megan, Dezi, Lindsay Ann, Untiveros, Gustavo, Strizzi, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099829/
https://www.ncbi.nlm.nih.gov/pubmed/35563300
http://dx.doi.org/10.3390/ijms23094904