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Role of Presenilin-1 in Aggressive Human Melanoma
Presenilin-1 (PS-1), a component of the gamma (γ)-secretase catalytic complex, has been implicated in Alzheimer’s disease (AD) and in tumorigenesis. Interestingly, AD risk is inversely related to melanoma, suggesting that AD-related factors, such as PS-1, may affect melanomagenesis. PS-1 has been sh...
Autores principales: | Sidor, Julia, Gillette, Megan, Dezi, Lindsay Ann, Untiveros, Gustavo, Strizzi, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099829/ https://www.ncbi.nlm.nih.gov/pubmed/35563300 http://dx.doi.org/10.3390/ijms23094904 |
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