One-Pot Synthesis of (E)-2-(3-Oxoindolin-2-ylidene)-2-arylacetonitriles

A highly efficient and expeditious one-pot approach towards 2-(3-oxoindolin-2-yl)acetonitriles was designed, which involves a base-assisted aldol reaction of ortho-nitroacetophenones, followed by hydrocyanation, triggering an unusual reductive cyclization reaction.

Detalles Bibliográficos
Autores principales: Aksenov, Nicolai A., Aksenov, Alexander V., Kurenkov, Igor A., Kirillov, Nikita K., Aksenov, Dmitrii A., Arutiunov, Nikolai A., Aksenova, Daria S., Rubin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099830/
https://www.ncbi.nlm.nih.gov/pubmed/35566159
http://dx.doi.org/10.3390/molecules27092808

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099830/
https://www.ncbi.nlm.nih.gov/pubmed/35566159
http://dx.doi.org/10.3390/molecules27092808

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