EMT, Stemness, and Drug Resistance in Biological Context: A 3D Tumor Tissue/In Silico Platform for Analysis of Combinatorial Treatment in NSCLC with Aggressive KRAS-Biomarker Signatures

SIMPLE SUMMARY: The phenotypic transition of tumor cells from epithelial to mesenchymal characteristics is called EMT and is widely discussed in the scientific community as a game changer in drug resistance and metastasis formation. However, clinical studies could not prove the efficacy of EMT-inter...

Descripción completa

Detalles Bibliográficos
Autores principales: Peindl, Matthias, Göttlich, Claudia, Crouch, Samantha, Hoff, Niklas, Lüttgens, Tamara, Schmitt, Franziska, Pereira, Jesús Guillermo Nieves, May, Celina, Schliermann, Anna, Kronenthaler, Corinna, Cheufou, Danjouma, Reu-Hofer, Simone, Rosenwald, Andreas, Weigl, Elena, Walles, Thorsten, Schüler, Julia, Dandekar, Thomas, Nietzer, Sarah, Dandekar, Gudrun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099837/
https://www.ncbi.nlm.nih.gov/pubmed/35565305
http://dx.doi.org/10.3390/cancers14092176

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099837/
https://www.ncbi.nlm.nih.gov/pubmed/35565305
http://dx.doi.org/10.3390/cancers14092176

Ejemplares similares