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Pancreatic Ductal Cell-Derived Extracellular Vesicles Are Effective Drug Carriers to Enhance Paclitaxel’s Efficacy in Pancreatic Cancer Cells through Clathrin-Mediated Endocytosis

Chemo-resistance challenges the clinical management of pancreatic ductal adenocarcinoma (PDAC). A limited admittance of chemotherapeutics to PDAC tissues is a key obstacle in chemotherapy of the malignancy. An enhanced uptake of drugs into PDAC cells is required for a more effective treatment. Extra...

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Detalles Bibliográficos
Autores principales: Sun, Haoyao, Bhandari, Kritisha, Burrola, Stephanie, Wu, Jinchang, Ding, Wei-Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099870/
https://www.ncbi.nlm.nih.gov/pubmed/35563165
http://dx.doi.org/10.3390/ijms23094773