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Effects of Two Natural Bisbenzylisoquinolines, Curine and Guattegaumerine, Extracted from Isolona hexaloba on Rhodamine Efflux by Abcb1b from Rat Glycocholic-Acid-Resistant Hepatocarcinoma Cells

To develop new therapeutic molecules, it is essential to understand the biological effects and targets of clinically relevant compounds. In this article, we describe the extraction and characterization of two alkaloids from the roots of Isolona hexaloba—curine and guattegaumerine. The effect of thes...

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Detalles Bibliográficos
Autores principales: Sergent, Jacques-Aurélien, Mathouet, Hilarion, Hulen, Christian, Lameiras, Pedro, Feuilloley, Marc, Elomri, Abdelhakim, Lomri, Nour-Eddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9099951/
https://www.ncbi.nlm.nih.gov/pubmed/35566380
http://dx.doi.org/10.3390/molecules27093030