First Characterization of Human Dermal Fibroblasts Showing a Decreased Xylosyltransferase-I Expression Induced by the CRISPR/Cas9 System

Background: Xylosyltransferases-I and II (XT-I and XT-II) catalyze the initial and rate limiting step of the proteoglycan (PG) biosynthesis and therefore have an import impact on the homeostasis of the extracellular matrix (ECM). The reason for the occurrence of two XT-isoforms in all higher organis...

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Detalles Bibliográficos
Autores principales: Fischer, Bastian, Schmidt, Vanessa, Ly, Thanh-Diep, Kleine, Anika, Knabbe, Cornelius, Faust-Hinse, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100032/
https://www.ncbi.nlm.nih.gov/pubmed/35563435
http://dx.doi.org/10.3390/ijms23095045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100032/
https://www.ncbi.nlm.nih.gov/pubmed/35563435
http://dx.doi.org/10.3390/ijms23095045

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