Modulation of the MOP Receptor (μ Opioid Receptor) by Imidazo[1,2-a]imidazole-5,6-Diones: In Search of the Elucidation of the Mechanism of Action

The μ-opioid receptors belong to the family of G protein-coupled receptors (GPCRs), and their activation triggers a cascade of intracellular relays with the final effect of analgesia. Classical agonists of this receptor, such as morphine, are the main targets in the treatment of both acute and chron...

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Detalles Bibliográficos
Autores principales: Straszak, Dominik, Siwek, Agata, Głuch-Lutwin, Monika, Mordyl, Barbara, Kołaczkowski, Marcin, Pietrzak, Aldona, Rahnama-Hezavah, Mansur, Drop, Bartłomiej, Matosiuk, Dariusz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100072/
https://www.ncbi.nlm.nih.gov/pubmed/35566280
http://dx.doi.org/10.3390/molecules27092930

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100072/
https://www.ncbi.nlm.nih.gov/pubmed/35566280
http://dx.doi.org/10.3390/molecules27092930

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