Cargando…

Physosmotic Induction of Chondrogenic Maturation Is TGF-β Dependent and Enhanced by Calcineurin Inhibitor FK506

Increasing extracellular osmolarity 100 mOsm/kg above plasma level to the physiological levels for cartilage induces chondrogenic marker expression and the differentiation of chondroprogenitor cells. The calcineurin inhibitor FK506 has been reported to modulate the hypertrophic differentiation of pr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jahr, Holger, van der Windt, Anna E., Timur, Ufuk Tan, Baart, Esther B., Lian, Wei-Shiung, Rolauffs, Bernd, Wang, Feng-Sheng, Pufe, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100228/ https://www.ncbi.nlm.nih.gov/pubmed/35563498 http://dx.doi.org/10.3390/ijms23095110

Ejemplares similares

Novel inhibitors of the calcineurin/NFATc hub - alternatives to CsA and FK506?
por: Sieber, Matthias, et al.
Publicado: (2009)

FK506 reduces calpain-regulated calcineurin activity in both the cytoplasm and the nucleus
por: Lee, Sun Hee, et al.
Publicado: (2014)

Treatment With Calcineurin Inhibitor FK506 Attenuates Noise-Induced Hearing Loss
por: He, Zu-Hong, et al.
Publicado: (2021)

FK506 Induces the TGF-β1/Smad 3 Pathway Independently of Calcineurin Inhibition to Prevent Intervertebral Disk Degeneration
por: Ge, Jun, et al.
Publicado: (2020)

Inhibition of calcineurin by FK506 stimulates germinal vesicle breakdown of mouse oocytes in hypoxanthine-supplemented medium
por: Wang, Li, et al.
Publicado: (2017)

Interactions of FK506 and Rapamycin With FK506 Binding Protein 12 in Opportunistic Human Fungal Pathogens
por: Vellanki, Sandeep, et al.
Publicado: (2020)

Maculopathy Associated with Tacrolimus (FK 506)
por: Koh, Taehyuk, et al.
Publicado: (2011)

Pathogenic virus-specific T cells cause disease during treatment with the calcineurin inhibitor FK506: implications for transplantation
por: Araki, Koichi, et al.
Publicado: (2010)

The immunosuppressive and toxic effects of FK-506 are mechanistically related: pharmacology of a novel antagonist of FK-506 and rapamycin
Publicado: (1992)

The Calcineurin Inhibitor FK506 Prevents Cognitive Impairment by Inhibiting Reactive Astrogliosis in Pilocarpine-Induced Status Epilepticus Rats
por: Liu, Jinzhi, et al.
Publicado: (2018)

Harnessing calcineurin-FK506-FKBP12 crystal structures from invasive fungal pathogens to develop antifungal agents
por: Juvvadi, Praveen R., et al.
Publicado: (2019)

Leveraging Fungal and Human Calcineurin-Inhibitor Structures, Biophysical Data, and Dynamics To Design Selective and Nonimmunosuppressive FK506 Analogs
por: Gobeil, Sophie M.-C., et al.
Publicado: (2021)

The Effect of FK 506 on the Reepithelialization of Superficial Skin Wound
por: Shin, Jeong Min, et al.
Publicado: (2017)

Effects of FK506 on Ca(2+) Release Channels (Review)
por: Ozawa, Terutaka
Publicado: (2008)

Molecular Evolution of the Vertebrate FK506 Binding Protein 25
por: Liu, Fei, et al.
Publicado: (2014)

FK506 attenuates thymic output in patients with myasthenia gravis
por: Mitsui, Takao, et al.
Publicado: (2013)

FK506 immunosuppression for submandibular salivary gland allotransplantation in rabbit
por: Almansoori, Akram Abdo, et al.
Publicado: (2020)

Role of FK506-sensitive signals in asthmatic lung inflammation
por: Tomiaki, Chihiro, et al.
Publicado: (2022)

FK506-Binding Protein 2 Participates in Proinsulin Folding
por: Hoefner, Carolin, et al.
Publicado: (2023)

49. Recruited Macrophages are Required for Neuroenhancing Effects of Fk506
por: Broberg, Curtis, et al.
Publicado: (2023)

Advancing Nerve Regeneration: Translational Perspectives of Tacrolimus (FK506)
por: Daeschler, Simeon C., et al.
Publicado: (2023)

FK506-binding protein-like and FK506-binding protein 8 regulate dual leucine zipper kinase degradation and neuronal responses to axon injury
por: Lee, Bohm, et al.
Publicado: (2022)

An improved reversibly dimerizing mutant of the FK506-binding protein FKBP
por: Barrero, Juan J., et al.
Publicado: (2016)

Abstract 134: FK506 Delivering Conduit For Peripheral Nerve Regeneration
por: Labroo, Pratima, et al.
Publicado: (2017)

Targeted Covalent Inhibition of Plasmodium FK506 Binding Protein 35
por: Atack, Thomas C., et al.
Publicado: (2020)

FK506 Attenuated Pilocarpine-Induced Epilepsy by Reducing Inflammation in Rats
por: Wang, Aihua, et al.
Publicado: (2019)

FK506 increases susceptibility to musculoskeletal infection in a rodent model
por: Shiels, Stefanie M., et al.
Publicado: (2022)

Optimization of the precursor supply for an enhanced FK506 production in Streptomyces tsukubaensis
por: Schulz, Susann, et al.
Publicado: (2022)

Development of Non-Immunosuppressive FK506 Derivatives as Antifungal and Neurotrophic Agents
por: Jung, Jin A, et al.
Publicado: (2020)

FK506-binding protein 51 is a possible novel tumoral marker
por: Romano, S, et al.
Publicado: (2010)

Genome-Wide Screening for Genes Associated with FK506 Sensitivity in Fission Yeast
por: Ma, Yan, et al.
Publicado: (2011)

Neuroprotective effects of Tacrolimus (FK-506) and Cyclosporin (CsA) in oxidative injury
por: Yousuf, Seema, et al.
Publicado: (2011)

The Emerging Role of Large Immunophilin FK506 Binding Protein 51 in Cancer
por: Romano, S, et al.
Publicado: (2011)

FK506 biosynthesis is regulated by two positive regulatory elements in Streptomyces tsukubaensis
por: Goranovič, Dušan, et al.
Publicado: (2012)

Analysing the visible conformational substates of the FK506-binding protein FKBP12
por: Mustafi, Sourajit M., et al.
Publicado: (2013)

Impairment of early fracture healing by skeletal muscle trauma is restored by FK506
por: Hurtgen, Brady J., et al.
Publicado: (2017)

A case of reversible toxic optic neuropathy from tacrolimus (FK506)
por: Gokoffski, Kimberly K., et al.
Publicado: (2020)

EFFECTS OF FK506 ON THE HEALING OF DIAPHYSEAL, CRITICAL SIZE DEFECTS IN THE RAT FEMUR
por: De la Vega, R.E., et al.
Publicado: (2020)

FK506-binding protein 5 promotes the progression of papillary thyroid carcinoma
por: Gao, Zhenya, et al.
Publicado: (2021)

Optimization of FK-506 production in Streptomyces tsukubaensis by modulation of Crp-mediated regulation
por: Schulz, Susann, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_7jppudschv8qp7mthjhlhlf3l5