Loss of Proximal Tubular Sirtuin 6 Aggravates Unilateral Ureteral Obstruction-Induced Tubulointerstitial Inflammation and Fibrosis by Regulation of β-Catenin Acetylation

Renal fibrosis is a significant pathologic change associated with progressive kidney disease. Sirt6 is an NAD(+)-dependent deacetylase and mono-ADP ribosyltransferase known to play diverse roles in the processes attendant to aging, metabolism, and carcinogenesis. However, the role of proximal tubule...

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Detalles Bibliográficos
Autores principales: Jin, Jixiu, Li, Wenjia, Wang, Tian, Park, Byung-Hyun, Park, Sung Kwang, Kang, Kyung Pyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100256/
https://www.ncbi.nlm.nih.gov/pubmed/35563783
http://dx.doi.org/10.3390/cells11091477

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100256/
https://www.ncbi.nlm.nih.gov/pubmed/35563783
http://dx.doi.org/10.3390/cells11091477

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