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Loss of Proximal Tubular Sirtuin 6 Aggravates Unilateral Ureteral Obstruction-Induced Tubulointerstitial Inflammation and Fibrosis by Regulation of β-Catenin Acetylation

Renal fibrosis is a significant pathologic change associated with progressive kidney disease. Sirt6 is an NAD(+)-dependent deacetylase and mono-ADP ribosyltransferase known to play diverse roles in the processes attendant to aging, metabolism, and carcinogenesis. However, the role of proximal tubule...

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Detalles Bibliográficos
Autores principales:	Jin, Jixiu, Li, Wenjia, Wang, Tian, Park, Byung-Hyun, Park, Sung Kwang, Kang, Kyung Pyo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100256/ https://www.ncbi.nlm.nih.gov/pubmed/35563783 http://dx.doi.org/10.3390/cells11091477

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