Functional Rescue of Inactivating Mutations of the Human Neurokinin 3 Receptor Using Pharmacological Chaperones

G protein-coupled receptors (GPCRs) facilitate the majority of signal transductions across cell membranes in humans, with numerous diseases attributed to inactivating GPCR mutations. Many of these mutations result in misfolding during nascent receptor synthesis in the endoplasmic reticulum (ER), res...

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Detalles Bibliográficos
Autores principales: Anderson, Ross C., Hanyroup, Sharika, Song, Yong Bhum, Mohamed-Moosa, Zulfiah, van den Bout, Iman, Schwulst, Alexis C., Kaiser, Ursula B., Millar, Robert P., Newton, Claire L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100388/
https://www.ncbi.nlm.nih.gov/pubmed/35562976
http://dx.doi.org/10.3390/ijms23094587

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100388/
https://www.ncbi.nlm.nih.gov/pubmed/35562976
http://dx.doi.org/10.3390/ijms23094587

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