Stereocontrolled Total Synthesis of Bastimolide B Using Iterative Homologation of Boronic Esters

[Image: see text] Bastimolide B is a polyhydroxy macrolide isolated from marine cyanobacteria displaying antimalarial activity. It features a dense array of hydroxylated stereogenic centers with 1,5-relationships along a hydrocarbon chain. These 1,5-polyols represent a particularly challenging motif...

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Detalles Bibliográficos
Autores principales: Fiorito, Daniele, Keskin, Selbi, Bateman, Joseph M., George, Malcolm, Noble, Adam, Aggarwal, Varinder K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100475/
https://www.ncbi.nlm.nih.gov/pubmed/35499478
http://dx.doi.org/10.1021/jacs.2c03192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100475/
https://www.ncbi.nlm.nih.gov/pubmed/35499478
http://dx.doi.org/10.1021/jacs.2c03192

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