Molecular Pathogenesis of Myeloproliferative Neoplasms: From Molecular Landscape to Therapeutic Implications

Despite distinct clinical entities, the myeloproliferative neoplasms (MPN) share morphological similarities, propensity to thrombotic events and leukemic evolution, and a complex molecular pathogenesis. Well-known driver mutations, JAK2, MPL and CALR, determining constitutive activation of JAK-STAT...

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Detalles Bibliográficos
Autores principales: Morsia, Erika, Torre, Elena, Poloni, Antonella, Olivieri, Attilio, Rupoli, Serena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100530/
https://www.ncbi.nlm.nih.gov/pubmed/35562964
http://dx.doi.org/10.3390/ijms23094573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100530/
https://www.ncbi.nlm.nih.gov/pubmed/35562964
http://dx.doi.org/10.3390/ijms23094573

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