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Targeting Ribosome Biogenesis in Cancer: Lessons Learned and Way Forward

SIMPLE SUMMARY: Cells need to produce ribosomes to sustain continuous proliferation and expand in numbers, a feature that is even more prominent in uncontrollably proliferating cancer cells. Certain cancer cell types are expected to depend more on ribosome biogenesis based on their genetic backgroun...

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Detalles Bibliográficos
Autores principales: Zisi, Asimina, Bartek, Jiri, Lindström, Mikael S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100539/
https://www.ncbi.nlm.nih.gov/pubmed/35565259
http://dx.doi.org/10.3390/cancers14092126