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Zwitterionic Modification of Polyethyleneimine for Efficient In Vitro siRNA Delivery
Polyethylenimine (PEI) has been widely used in gene delivery. However, its high cytotoxicity and undesired non-specific protein adsorption hinder the overall delivery efficacy and the practical applications of PEI-based gene delivery systems. In this study, we prepared hydrophobically modified PEIs...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100541/ https://www.ncbi.nlm.nih.gov/pubmed/35563405 http://dx.doi.org/10.3390/ijms23095014 |