Cargando…

Zwitterionic Modification of Polyethyleneimine for Efficient In Vitro siRNA Delivery

Polyethylenimine (PEI) has been widely used in gene delivery. However, its high cytotoxicity and undesired non-specific protein adsorption hinder the overall delivery efficacy and the practical applications of PEI-based gene delivery systems. In this study, we prepared hydrophobically modified PEIs...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Fengfan, Su, Huahui, Li, Mengqian, Xie, Wanxuan, Yan, Yunfeng, Shuai, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100541/
https://www.ncbi.nlm.nih.gov/pubmed/35563405
http://dx.doi.org/10.3390/ijms23095014