Intron-Encoded Domain of Herstatin, An Autoinhibitor of Human Epidermal Growth Factor Receptors, Is Intrinsically Disordered

Human epidermal growth factor receptors (HER/ERBB) form dimers that promote cell proliferation, migration, and differentiation, but overexpression of HER proteins results in cancer. Consequently, inhibitors of HER dimerization may function as effective antitumor drugs. An alternatively spliced varia...

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Detalles Bibliográficos
Autores principales: Tashiro, Daisuke, Suetaka, Shunji, Sato, Nao, Ooka, Koji, Kunihara, Tomoko, Kudo, Hisashi, Inatomi, Junichi, Hayashi, Yuuki, Arai, Munehito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100580/
https://www.ncbi.nlm.nih.gov/pubmed/35573740
http://dx.doi.org/10.3389/fmolb.2022.862910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100580/
https://www.ncbi.nlm.nih.gov/pubmed/35573740
http://dx.doi.org/10.3389/fmolb.2022.862910

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