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An Insight into the Medicinal Chemistry Perspective of Macrocyclic Derivatives with Antitumor Activity: A Systematic Review

The profound pharmacological properties of macrocyclic compounds have led to their development as drugs. In conformationally pre-organized ring structures, the multiple functions and stereochemical complexity provided by the macrocycle result in high affinity and selectivity of protein targets while...

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Detalles Bibliográficos
Autores principales: Liang, Yan, Fang, Ru, Rao, Qiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100616/
https://www.ncbi.nlm.nih.gov/pubmed/35566196
http://dx.doi.org/10.3390/molecules27092837