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Focused Design of Novel Cyclic Peptides Endowed with GABARAP-Inhibiting Activity

(1) Background: Disfunctions in autophagy machinery have been identified in various conditions, including neurodegenerative diseases, cancer, and inflammation. Among mammalian autophagy proteins, the Atg8 family member GABARAP has been shown to be greatly involved in the autophagy process of prostat...

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Detalles Bibliográficos
Autores principales: Fassi, Enrico Mario Alessandro, Garofalo, Mariangela, Sgrignani, Jacopo, Dei Cas, Michele, Mori, Matteo, Roda, Gabriella, Cavalli, Andrea, Grazioso, Giovanni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100651/
https://www.ncbi.nlm.nih.gov/pubmed/35563459
http://dx.doi.org/10.3390/ijms23095070