NGF Modulates Cholesterol Metabolism and Stimulates ApoE Secretion in Glial Cells Conferring Neuroprotection against Oxidative Stress

Cholesterol plays a crucial role in the brain, where its metabolism is particularly regulated by astrocytic activity. Indeed, adult neurons suppress their own cholesterol biosynthesis and import this sterol through ApoE-rich particles secreted from astrocytes. Recent evidence suggests that nerve gro...

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Detalles Bibliográficos
Autores principales: Colardo, Mayra, Petraroia, Michele, Lerza, Letizia, Pensabene, Daniele, Martella, Noemi, Pallottini, Valentina, Segatto, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100774/
https://www.ncbi.nlm.nih.gov/pubmed/35563230
http://dx.doi.org/10.3390/ijms23094842

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100774/
https://www.ncbi.nlm.nih.gov/pubmed/35563230
http://dx.doi.org/10.3390/ijms23094842

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