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The Role of Extracellular Matrix Components in the Spreading of Pathological Protein Aggregates
Several neurodegenerative diseases are characterized by the accumulation of aggregated misfolded proteins. These pathological agents have been suggested to propagate in the brain via mechanisms similar to that observed for the prion protein, where a misfolded variant is transferred from an affected...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100790/ https://www.ncbi.nlm.nih.gov/pubmed/35573838 http://dx.doi.org/10.3389/fncel.2022.844211 |