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The Role of Extracellular Matrix Components in the Spreading of Pathological Protein Aggregates

Several neurodegenerative diseases are characterized by the accumulation of aggregated misfolded proteins. These pathological agents have been suggested to propagate in the brain via mechanisms similar to that observed for the prion protein, where a misfolded variant is transferred from an affected...

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Detalles Bibliográficos
Autores principales:	Moretto, Edoardo, Stuart, Skye, Surana, Sunaina, Vargas, Jose Norberto S., Schiavo, Giampietro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100790/ https://www.ncbi.nlm.nih.gov/pubmed/35573838 http://dx.doi.org/10.3389/fncel.2022.844211

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