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Solvent Vibrations as a Proxy of the Telomere G-Quadruplex Rearrangements across Thermal Unfolding

G-quadruplexes (G4s) are noncanonical forms of DNA involved in many key genome functions. Here, we exploited UV Resonance Raman scattering to simultaneously explore the vibrational behavior of a human telomeric G4 (Tel22) and its aqueous solvent as the biomolecule underwent thermal melting. We found...

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Detalles Bibliográficos
Autores principales: Libera, Valeria, Bianchi, Federico, Rossi, Barbara, D’Amico, Francesco, Masciovecchio, Claudio, Petrillo, Caterina, Sacchetti, Francesco, Paciaroni, Alessandro, Comez, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100830/
https://www.ncbi.nlm.nih.gov/pubmed/35563512
http://dx.doi.org/10.3390/ijms23095123