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LDH-A—Modulation and the Variability of LDH Isoenzyme Profiles in Murine Gliomas: A Link with Metabolic and Growth Responses

SIMPLE SUMMARY: Three different murine glioma cell lines were modified to downregulate the expression of the murine LDH-A gene using shRNA knock-down (KD), and compared to shRNA scrambled control (NC) cell lines. Successful LDH-A KD was confirmed by differences in the expression of LDH-A and LDH-B m...

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Detalles Bibliográficos
Autores principales: Shindo, Masahiro, Maeda, Masatomo, Myat, Ko, Mane, Mayuresh M., Cohen, Ivan J., Vemuri, Kiranmayi, Albeg, Avi S., Serganova, Inna, Blasberg, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100845/
https://www.ncbi.nlm.nih.gov/pubmed/35565432
http://dx.doi.org/10.3390/cancers14092303