Engineering CRISPR/Cas9 for Multiplexed Recombinant Coagulation Factor Production

Current hemostatic agents are obtained from pooled plasma from multiple donors requiring costly pathogen screening and processing. Recombinant DNA-based production represents an engineering solution that could improve supply, uniformity, and safety. Current approaches are typically for single gene c...

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Detalles Bibliográficos
Autores principales: Feser, Colby J., Lees, Christopher J., Lammers, Daniel T., Riddle, Megan J., Bingham, Jason R., Eckert, Matthew J., Tolar, Jakub, Osborn, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100926/
https://www.ncbi.nlm.nih.gov/pubmed/35563479
http://dx.doi.org/10.3390/ijms23095090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100926/
https://www.ncbi.nlm.nih.gov/pubmed/35563479
http://dx.doi.org/10.3390/ijms23095090

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