Single-Nucleotide Variations, Insertions/Deletions and Copy Number Variations in Myelodysplastic Syndrome during Disease Progression Revealed by a Single-Cell DNA Sequencing Platform

SIMPLE SUMMARY: Myelodysplastic syndrome (MDS) is a myeloid neoplasm associated with complex clonal architecture. The application of single-cell sequencing is capable of revealing the clonal dynamics of MDS during disease progression and treatment resistance. This has advantages over bulk-tumor sequ...

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Detalles Bibliográficos
Autores principales: Lee, Paul, Yim, Rita, Fung, Sin-Hang, Miu, Kai-Kei, Wang, Zhangting, Wu, Ka-Chun, Au, Lester, Leung, Garret Man-Kit, Lee, Victor Ho-Fun, Gill, Harinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100947/
https://www.ncbi.nlm.nih.gov/pubmed/35563039
http://dx.doi.org/10.3390/ijms23094647

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9100947/
https://www.ncbi.nlm.nih.gov/pubmed/35563039
http://dx.doi.org/10.3390/ijms23094647

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