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Consequences of Chromosome Loss: Why Do Cells Need Each Chromosome Twice?

Aneuploidy is a cellular state with an unbalanced chromosome number that deviates from the usual euploid status. During evolution, elaborate cellular mechanisms have evolved to maintain the correct chromosome content over generations. The rare errors often lead to cell death, cell cycle arrest, or i...

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Detalles Bibliográficos
Autores principales: Chunduri, Narendra Kumar, Barthel, Karen, Storchova, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101035/
https://www.ncbi.nlm.nih.gov/pubmed/35563836
http://dx.doi.org/10.3390/cells11091530