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A Sensitive LC-MS/MS Method for the Simultaneous Determination of Two Thia-Analogous Indirubin N-Glycosides and Indirubin-3′-Monoxime in Plasma and Cell Culture Medium

Indirubin was identified as an active component of Danggui Longhui Wan, an herbal mixture used in traditional Chinese medicine, and showed anticancer activity in clinical trials in patients with chronic leukemia. Investigations on the mechanisms of antitumor action of indirubins have mainly focused...

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Detalles Bibliográficos
Autores principales: Fischle, Alica, Schwarz, Rico, Wendt, Franziska, Kordt, Marcel, Ramer, Robert, Boeckmann, Lars, Hein, Martin, Langer, Peter, Emmert, Steffen, Vollmar, Brigitte, Hinz, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101087/
https://www.ncbi.nlm.nih.gov/pubmed/35566381
http://dx.doi.org/10.3390/molecules27093031