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Transcriptomic and Proteomic Analysis of CRISPR/Cas9-Mediated ARC-Knockout HEK293 Cells

Arc/Arg3.1 (activity-regulated cytoskeletal-associated protein (ARC)) is a critical regulator of long-term synaptic plasticity and is involved in the pathophysiology of schizophrenia. The functions and mechanisms of human ARC action are poorly understood and worthy of further investigation. To inves...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Yuan, Hsu, Shih-Hsin, Tsai, Hsin-Yao, Cheng, Fu-Yu, Cheng, Min-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101110/
https://www.ncbi.nlm.nih.gov/pubmed/35562887
http://dx.doi.org/10.3390/ijms23094498