Astrocytes Derived from Familial and Sporadic Alzheimer’s Disease iPSCs Show Altered Calcium Signaling and Respond Differently to Misfolded Protein Tau

Astrocytes regulate important functions in the brain, and their dysregulation has been linked to the etiology of neurodegenerative diseases, such as Alzheimer’s disease (AD). The role of astroglia in human AD remains enigmatic, owing to the limitations of animal models, which, while recreating some...

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Detalles Bibliográficos
Autores principales: Brezovakova, Veronika, Sykova, Eva, Jadhav, Santosh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101114/
https://www.ncbi.nlm.nih.gov/pubmed/35563735
http://dx.doi.org/10.3390/cells11091429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101114/
https://www.ncbi.nlm.nih.gov/pubmed/35563735
http://dx.doi.org/10.3390/cells11091429

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