Rap1a Activity Elevated the Impact of Endogenous AGEs in Diabetic Collagen to Stimulate Increased Myofibroblast Transition and Oxidative Stress

Diabetics have an increased risk for heart failure due to cardiac fibroblast functional changes occurring as a result of AGE/RAGE signaling. Advanced glycation end products (AGEs) levels are higher in diabetics and stimulate elevated RAGE (receptor for AGE) signaling. AGE/RAGE signaling can alter th...

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Detalles Bibliográficos
Autores principales: Burr, Stephanie D., Dorroh, Christopher C., Stewart, James A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101126/
https://www.ncbi.nlm.nih.gov/pubmed/35562872
http://dx.doi.org/10.3390/ijms23094480

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101126/
https://www.ncbi.nlm.nih.gov/pubmed/35562872
http://dx.doi.org/10.3390/ijms23094480

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