The E3 Ubiquitin Ligase Fbxo4 Functions as a Tumor Suppressor: Its Biological Importance and Therapeutic Perspectives

SIMPLE SUMMARY: Fbxo4 is an E3 ubiquitin ligase that requires the formation of a complex with S-phase kinase-associated protein 1 and Cullin1 to catalyze the ubiquitylation of its substrates. Moreover, Fbxo4 depends on the existence of posttranslational modifications and/or co-factor to be activated...

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Detalles Bibliográficos
Autor principal: Qie, Shuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101129/
https://www.ncbi.nlm.nih.gov/pubmed/35565262
http://dx.doi.org/10.3390/cancers14092133

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101129/
https://www.ncbi.nlm.nih.gov/pubmed/35565262
http://dx.doi.org/10.3390/cancers14092133

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