Cyclic-AMP Increases Nuclear Actin Monomer Which Promotes Proteasomal Degradation of RelA/p65 Leading to Anti-Inflammatory Effects

The second messenger, cAMP has potent immunosuppressive and anti-inflammatory actions. These have been attributed, in part, to the ability of cAMP-induced signals to interfere with the function of the proinflammatory transcription factor Nuclear Factor-kappa B (NF-κB). However, the mechanisms underl...

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Detalles Bibliográficos
Autores principales: Hawkins, Joseph W., McNeill, Madeleine C., Ebrahimighaei, Reza, Mellor, Harry H., Newby, Andrew C., Bond, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101168/
https://www.ncbi.nlm.nih.gov/pubmed/35563720
http://dx.doi.org/10.3390/cells11091414

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101168/
https://www.ncbi.nlm.nih.gov/pubmed/35563720
http://dx.doi.org/10.3390/cells11091414

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