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Long-Distance Repression by Human Silencers: Chromatin Interactions and Phase Separation in Silencers

Three-dimensional genome organization represents an additional layer in the epigenetic regulation of gene expression. Active transcription controlled by enhancers or super-enhancers has been extensively studied. Enhancers or super-enhancers can recruit activators or co-activators to activate target...

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Detalles Bibliográficos
Autores principales: Zhang, Ying, See, Yi Xiang, Tergaonkar, Vinay, Fullwood, Melissa Jane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101175/
https://www.ncbi.nlm.nih.gov/pubmed/35563864
http://dx.doi.org/10.3390/cells11091560