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Effect of Cardiotonic Steroid Marinobufagenin on Vascular Remodeling and Cognitive Impairment in Young Dahl-S Rats

The hypertensive response in Dahl salt-sensitive (DSS) rats on a high-salt (HS) diet is accompanied by central arterial stiffening (CAS), a risk factor for dementia, and heightened levels of a prohypertensive and profibrotic factor, the endogenous Na/K-ATPase inhibitor marinobufagenin (MBG). We stud...

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Detalles Bibliográficos
Autores principales: Grigorova, Yulia N., Juhasz, Ondrej, Long, Jeffrey M., Zernetkina, Valentina I., Hall, Mikayla L., Wei, Wen, Morrell, Christopher H., Petrashevskaya, Natalia, Morrow, Audrey, LaNasa, Katherine H., Bagrov, Alexei Y., Rapp, Peter R., Lakatta, Edward G., Fedorova, Olga V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101263/
https://www.ncbi.nlm.nih.gov/pubmed/35562955
http://dx.doi.org/10.3390/ijms23094563