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Context-dependant enhancers as a reservoir of functional polymorphisms and epigenetic markers linked to alcohol use disorders and comorbidities
Alcohol use disorder (AUD) is one of the major causes of mortality and morbidity world-wide. It is estimated that 50% of the causes of AUD are heritable. Efforts to determine the genetic determinants governing AUD using genome wide association studies (GWAS) show that the most strongly associated SN...
Autores principales: | MacKenzie, Alasdair, Hay, Elizabeth A., McEwan, Andrew R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101288/ https://www.ncbi.nlm.nih.gov/pubmed/35712020 http://dx.doi.org/10.1016/j.addicn.2022.100014 |
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