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Design of DNA Intercalators Based on 4-Carboranyl-1,8-Naphthalimides: Investigation of Their DNA-Binding Ability and Anticancer Activity

In the present study, we continue our work related to the synthesis of 1,8-naphthalimide and carborane conjugates and the investigation of their anticancer activity and DNA-binding ability. For this purpose, a series of 4-carboranyl-1,8-naphthalimide derivatives, mitonafide, and pinafide analogs wer...

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Detalles Bibliográficos
Autores principales: Rykowski, Sebastian, Gurda-Woźna, Dorota, Orlicka-Płocka, Marta, Fedoruk-Wyszomirska, Agnieszka, Giel-Pietraszuk, Małgorzata, Wyszko, Eliza, Kowalczyk, Aleksandra, Stączek, Paweł, Biniek-Antosiak, Katarzyna, Rypniewski, Wojciech, Olejniczak, Agnieszka B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9101373/
https://www.ncbi.nlm.nih.gov/pubmed/35562989
http://dx.doi.org/10.3390/ijms23094598